Frahm N, Nickle DC, Linde CH, Cohen DE, Zuñiga R, Lucchetti A, Roach T, Walker BD, Allen TM, Korber BT, Mullins JI, Brander C (2008). Increased detection of HIV-specific T cell responses by combination of central sequences with comparable immunogenicity. AIDS (London, England), 22(4), 447-56. (pubmed) (doi)
To evaluate the recognition of computationally designed, centralized HIV-1 antigens derived from clade B, C and group M sequences by individuals infected with HIV-1-M clades B and C.