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University
of Washington School
of Medicine, Department
of Microbiology
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| van 't Wout et al. Supplemental Data |
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Supplement S1. Gene groups up regulated (red) or down regulated (green) by HIV-1BRU infection of
CCRF-CEM cells. Genes involved in cell signaling and communication were mostly up regulated, whereas genes
involved in gene and protein expression were mostly down regulated.
 |
| Group |
Up (%) |
Down (%) |
Total (%) |
| Cell division |
4 (2) |
13 (5) |
17 (4) |
| Defense |
2 (1) |
3 (1) |
5 (1) |
| DNA binding |
1 (1) |
10 (4) |
11 (3) |
| Protein processing |
7 (4) |
11 (5) |
18 (4) |
| Ribosomal |
1 (1) |
6 (2) |
7 (2) |
| RNA binding |
2 (1) |
8 (3) |
10 (2) |
| RNA helicase |
0 (0) |
7 (3) |
7 (2) |
| Splicing |
0 (0) |
8 (3) |
8 (2) |
| Translation |
0 (0) |
10 (4) |
10 (2) |
| Transcription |
17 (10) |
31 (13) |
48 (12) |
| Enzyme |
22 (13) |
31 (13) |
53 (13) |
| Transporter |
8 (5) |
10 (4) |
18 (4) |
| Apoptosis |
3 (2) |
1 (0) |
4 (1) |
| Channel |
3 (2) |
1 (0) |
4 (1) |
| Kinase |
6 (4) |
4 (2) |
10 (2) |
| Ligand |
4 (2) |
0 (0) |
4 (1) |
| Phosphatase |
1 (1) |
4 (0) |
5 (1) |
| Receptor |
22 (13) |
8 (3) |
30 (7) |
| Transducer |
17 (10) |
8 (3) |
25 (6) |
| Adhesion |
4 (2) |
6 (2) |
10 (2) |
| Cytoskeleton |
11 (7) |
3 (1) |
14 (3) |
| Unknown |
30 (18) |
61 (25) |
91 (22) |
| Total |
165 |
244 |
409 |
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