Jim Mullins' Laboratory is located in the Rosen Building of South Lake Union. Our lab uses the techniques of molecular, computational, and virus biology to provide basic insights into the relationship between HIV and human hosts in an effort to fight to stop the AIDS pandemic.
We use a variety of techniques to understand the implications of HIV's extraordinary genetic diversity for the pathogenesis of AIDS and with the intention of applying this information to the development of more effective vaccines and therapies. These techniques include virology, molecular biological and statistical analysis of nucleotide sequences, and high-throughput array analysis of cellular transcription.
New Web Site! After a long time in development, our updated web site is now in place. Old content is still being integrated to our new look, but is still available via the same URLs and the site map.
2009 HIV-1 superinfection in the antiretroviral therapy era: are seroconcordant sexual partners at risk? PLoS ONE4e5690 pubmed
2009 Increased mutations in Env and Pol suggest greater HIV-1 replication in sputum-derived viruses compared with blood-derived viruses. AIDSEpub ahead of print 3 April, 2009 pubmed
2009 Variable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) response. PLoS Pathogens54e1000365 pubmed
2009 Monotypic HIV-1 Genotypes across the Uterine Cervix and in Blood Suggests Proliferation of Cells with Provirus. Journal of Virology836020-8 pubmed
2009 Emergence of Multiclass Drug-Resistance in HIV-2 in Antiretroviral-Treated Individuals in Senegal: Implications for HIV-2 Treatment in Resouce-Limited West Africa. Clinical Infectious Diseases482009 Jan 1 Epub ahead of print pubmed
